Cech
Liechtsteiner Medley Jenks Monreal
Elneny AMN
Willock
Saka Nketiah Smith-Rowe
That's pretty spot on for me. Although I think it might be worth starting Koscileny with a view to giving him 45 minutes. Bring Monreal off early as well. Later in the game potentially drop Elneny to CB and AMN into a full-back role, given the need to be careful with potential CBs for Southampton (Koscielny, Monreal, Lichtsteiner) during this defensive crisis.
Jenkinson Medley Kos Monreal
Elneny AMN
Willock
Saka Nketiah Smith-Rowe